Editor's Note Using patient-specific preoperative variables, a validated logistic regression model predicted transfusions in total hip and knee patients in this study. The model identified preoperative hemoglobin, total hip arthroplasty, and females 65 years of age and older as predictors of perioperative transfusions. The model also may help identify those…

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Editor's Note Ketamine does not decrease delirium or lower levels of pain in older adults after major surgery and might cause harm by inducing hallucinations and nightmares, this study finds. A total of 672 patients were randomly assigned to a placebo group (222 patients), a 0.5 mg/kg ketamine group (227),…

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Editor's Note The Food and Drug Administration (FDA) on April 27 issued a Safety Alert saying the agency had approved label changes on the use of general anesthetic and sedation drugs in children younger than 3 years. The changes include: A new warning that exposure to these drugs for lengthy…

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Editor's Note In this study, the use of preoperative and postoperative elements of a Perioperative Surgical Home model in total knee and hip patients was associated with improvements in operational outcomes. The study included 1,225 patients in a preintervention PSH group and 1,363 in a postintervention PSH group. Compared with…

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Editor's Note In this French study, the majority of ICU patients had at least one organ failure at the time of death. Of 698 patients analyzed, 84% had one or more organ failures and 89% required at least one organ support at the time of death. Deaths were considered unexpected…

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Editor's Note The combination of femoral and sciatic nerve blocks is the overall best approach to pain management after total knee arthroplasty, finds this meta-analysis. The best five modalities for pain at rest were: femoral/obturator, femoral/sciatic/obturator, lumbar plexus/sciatic, femoral/sciatic, and fascia iliaca compartment blocks. For reducing opioid consumption, the best…

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Editor's Note Conscious sedation is a safe and viable option for anesthesia in patients having transcatheter aortic valve replacement (TAVR), finds this study. The use of conscious sedation rather than general anesthesia was associated with: similar rates of adverse events (1.5% in both groups) shortened ICU (30 vs 96 hours)…

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Editor's Note Non-OR anesthesia (NORA) is a growing component of anesthesiology practice in the US, this study finds. The proportion of NORA cases overall increased from 28.3% in 2010 to 35.9% in 2014, and the proportion of NORA outpatient cases increased from 69.7% to 73.3%. Colonoscopy was the most common…

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Editor's Note For the National Patient Safety Foundation’s Patient Safety Awareness Week, March 12 to 18, certified registered nurse anesthetists (CRNAs) are urging surgical, obstetric, and chronic pain patients to learn about the risks and benefits of pain relief options available to them, including opioid and non-opioid treatments. Partnering with…

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Editor's Note Opting out of the Medicare rule that requires anesthesia to be administered with physician supervision has little or no effect on access to inpatient or outpatient surgery, this study finds. The researchers also found that opting out does not reduce costs, and in fact increases costs for inpatient…

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