Editor's Note
At 10 years, prostate cancer mortality was low irrespective of the treatment, and with no significant difference among monitoring (1.5 deaths/1,000 person years), surgery (0.9/1,000), or radiotherapy (0.7/1,000), finds this study.
Radical prostatectomy and external beam radiotherapy were associated with lower incidences of disease progression and metastases than was active monitoring; however, 44% of active monitoring patients did not receive radical treatment and avoided side effects.
Men with newly diagnosed, localized prostate cancer need to consider the trade-off between the short-term and long-term effects of radical treatment on urinary, bowel, and sexual function and the higher risk of disease progression as well as the effect of each option on quality of life, the authors say.
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