Antimicrobial sutures shown to prevent SSIs

Editor's Note

In this meta-analysis and trial sequential analysis, triclosan-coated sutures were shown to be effective in preventing surgical site infections (SSIs). A total of 21 randomized clinical trials, involving 6,462 patients, were included.

The meta-analysis found a risk of 138 SSIs per 1,000 procedures, and the use of triclosan-coated sutures reduced this by 39. Trial sequential analysis confirmed a relative risk reduction of 15%.

Systematic review Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands Search for more papers by this author Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands Search for more papers by this author Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA Search for more papers by this author Corresponding author Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands Correspondence to: Professor M.