Association of TAVR for bicuspid vs tricuspid aortic stenosis with mortality, stroke

Editor's Note

In this study, patients who had transcatheter aortic valve replacement (TAVR) for bicuspid compared with tricuspid aortic stenosis had no significant difference in mortality, but they had a 30-day increased risk of stroke.

In this cohort of 2,691 matched pairs of patients having TAVR for bicuspid vs tricuspid aortic stenosis, there was no significant difference in 30-day (2.6% vs 2.5%) or 1-year (10.5% vs 12.0%) mortality. However, the 30-day risk of stroke was significantly higher for those with bicuspid aortic stenosis (2.5% vs 1.6%).

The researchers concluded that randomized trials will be needed to adequately assess the efficacy and safety of TAVR for bicuspid aortic stenosis.