April 14, 2022

Physical activity linked to risk of depression

By: Judy Mathias
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Editor's Note

This systematic review and meta-analysis, led by researchers from the UK, finds that even relatively small doses of physical activity are associated with substantially lower risks of depression.

The analysis included 15 prospective studies comprising 191,130 participants and 2 million person-years.

The results show an inverse curvilinear association with the greatest differences in risk seen between low doses of physical activity, suggesting that individuals realize the most benefits when moving from no activity to at least some.

Building activity volume equivalent to 2.5 hours of brisk walking per week was tied to a 25% lower risk of depression. At half that volume, the risk was 18% lower compared with no activity. Only minor additional benefits were seen at higher activity levels.

The researchers concluded that healthcare practitioners should encourage increases in physical activity to improve mental health.

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