Study: standard preoperative fasting guidelines safe for GLP-1 patients

Editor's Note

Preoperative use of GLP-1 receptor agonists (RA) medications such as Ozempic and Wegovy is safe, according to a study published in the June issue of the American Journal of Gastroenterology.

Controversy has swirled around these drugs due to the risk of slowed stomach emptying increasing a patient’s odds of choking, according to a June 6 report on the study in the Northeast Mississippi Daily Journal. However, data from 15 randomized studies showed only a minimal impact on gastric emptying among GLP-1 users, suggesting continued safety before surgery with minor precautions, like abstaining from solid food for a day.

Guidelines on GLP-1 use prior to surgery vary, the outlet reports. Until further data is available, the review recommends updating guidelines to advise GLP-1 users to continue therapy, follow the conservative approach of a liquid-only diet the day before surgery, and adhere to standard pre-anesthesia fasting recommendations.