Transplant

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October 2024
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Opioid epidemic increases number of hearts available for transplant

Editor's Note The opioid epidemic has expanded the pool of overdose-death donors (ODDs) for heart transplantation. Even though ODDs have higher rates of hepatitis C, cardiac allograft quality indices are favorable, and recipient outcomes are similar to those with non-ODD hearts, this study finds. Of 15,904 heart transplant donors analyzed,…

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By: Judy Mathias
June 6, 2019
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Transplanting hearts, lungs from HCV-infected donors into recipients without HCV infection

Editor's Note In patients without HCV infection who received a heart or lung transplant from HCV-infected donors, treatment with a 4-week antiviral regimen prevented establishment of HCV infection, this study finds. Of 44 patients enrolled in the study, 36 received lung transplants and 8 received heart transplants. All of the…

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By: Judy Mathias
April 25, 2019
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First penis transplantation completed in the US

Editor's Note Surgeons at the Massachusetts General Hospital, Boston, completed the first successful penis transplantation in the US in a patient who had a subtotal penectomy for penile cancer. Operative reinterventions were needed on postoperative days 2 and 3 for hematoma evacuation and skin eschar debridement. At 3 weeks, no…

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By: Judy Mathias
April 26, 2018
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Vanderbilt heart transplant program reaches new record

Editor's Note Nashville's Vanderbilt University Medical Center (VUMC) performed a record number of heart transplants in 2017, making it the second-busiest heart transplant program in the country. VUMC performed a record 97 heart transplantations,  including pediatric cases, which surpassed the 2016 milestone of 92. Vanderbilt is building a program that…

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By: Judy Mathias
February 7, 2018
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Pediatric kidney transplant success rates improve

Editor's Note The success rates of pediatric kidney transplants have significantly improved over the past 50 years, with young children now experiencing better long-term transplant success than adults, this study finds. Of 1,056 pediatric kidney transplant recipients analyzed, 85% were alive at 1 year after surgery 50 years ago, compared…

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By: Judy Mathias
February 28, 2017
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Liver transplantation beneficial in critically ill children

Editor's Note Advances in critical care have made it possible for critically ill children to undergo liver transplantation with the same survival benefits as children who are stable before surgery, this study finds. At Texas Children’s Hospital, 65 of 354 patients who had liver transplantation between 2002 and 2015 were…

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By: Judy Mathias
February 8, 2017
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Effect of organ donor hospital volume on transplantable organs

Editor's Note Hospitals managing the highest volume of deceased organ donors were 52% more likely to recover an above-average number of transplantable organs per donor than low-volume hospitals in this study. The study included data from 4,427 donors across 384 hospitals. High-volume hospitals had an organ yield (ie, rate of…

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By: Judy Mathias
January 19, 2017
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Computer algorithm shows need for high-volume care for heart, lung transplant patients

Editor's Note Using a computerized mathematical model, Johns Hopkins researches investigated whether they could improve heart and lung transplants by transferring patients from low- to high-volume transplant centers. Among the findings: For heart transplants, 10 lives were saved after one center closure, and 240 lives were saved after up to…

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By: Judy Mathias
September 14, 2016
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First clinical trial of HCV-infected kidney transplants

Editor's Note Researchers at Penn Medicine, Philadelphia, are conducting a clinical trial to test the effect of administering antiviral therapy to organ recipients after being transplanted with kidneys infected with the hepatitis C virus (HCV). The first participant received a kidney transplant in July, and after being treated with Zepatier…

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By: Judy Mathias
September 13, 2016
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Growing number of sickest patients removed from liver transplant wait list

Editor's Note Liver transplant candidates who are the sickest and should be first in line for a donor liver are increasingly being removed from the wait list because they are considered too sick to transplant, finds this study. Between 2007 and 2012, more than 4,300 patients were taken off the…

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By: Judy Mathias
April 29, 2016
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