Editor's Note Researchers from Europe used an epigenetic clock to accurately measure biological aging in a clinical setting, Wiley October 12 reports. The study, titled "Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing," was published in the Journal of Internal Medicine. The researchers…
Editor's Note An 8-year-old girl in the UK has been able to live a normal life without immunosuppressants following a kidney transplant in which both the organ and stem cells came from the same donor, The Independent October 12 reports. The patient was able to stop taking immunosuppressant drugs a…
Editor's Note A quality improvement study led by clinicians at the Mayo Clinic in Jacksonville, FL, improved clinical alarm management skills and reduced alarm fatigue and desensitization among nurses in a surgical intensive care unit. The study included 115 direct-care nurses working full-time, modified full-time, or part-time schedules in a…
Editor's Note This study, led by researchers at the Smidt Heart Institute at Cedars-Sinai Medical Center, Los Angeles, finds that from August 2020 through September 2021, 7% of lung transplantations in the US were performed in patients with COVID-19-related respiratory failure. In this analysis of 3,039 lung transplants, 214 were…
Editor's Note This study led by researchers at the University of Texas Southwestern Medical Center, Dallas, finds that although COVID-19’s effect on access to liver transplantation has been all-pervasive, minorities have been disproportionately affected—especially those with public insurance. During the initial wave of COVID-19, organ transplantation was classified as a…
Editor's Note The opioid epidemic has expanded the pool of overdose-death donors (ODDs) for heart transplantation. Even though ODDs have higher rates of hepatitis C, cardiac allograft quality indices are favorable, and recipient outcomes are similar to those with non-ODD hearts, this study finds. Of 15,904 heart transplant donors analyzed,…
Editor's Note In patients without HCV infection who received a heart or lung transplant from HCV-infected donors, treatment with a 4-week antiviral regimen prevented establishment of HCV infection, this study finds. Of 44 patients enrolled in the study, 36 received lung transplants and 8 received heart transplants. All of the…
Editor's Note Surgeons at the Massachusetts General Hospital, Boston, completed the first successful penis transplantation in the US in a patient who had a subtotal penectomy for penile cancer. Operative reinterventions were needed on postoperative days 2 and 3 for hematoma evacuation and skin eschar debridement. At 3 weeks, no…
Editor's Note Nashville's Vanderbilt University Medical Center (VUMC) performed a record number of heart transplants in 2017, making it the second-busiest heart transplant program in the country. VUMC performed a record 97 heart transplantations, including pediatric cases, which surpassed the 2016 milestone of 92. Vanderbilt is building a program that…
Editor's Note The success rates of pediatric kidney transplants have significantly improved over the past 50 years, with young children now experiencing better long-term transplant success than adults, this study finds. Of 1,056 pediatric kidney transplant recipients analyzed, 85% were alive at 1 year after surgery 50 years ago, compared…