Editor's Note Advances in critical care have made it possible for critically ill children to undergo liver transplantation with the same survival benefits as children who are stable before surgery, this study finds. At Texas Children’s Hospital, 65 of 354 patients who had liver transplantation between 2002 and 2015 were…

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Editor's Note Hospitals managing the highest volume of deceased organ donors were 52% more likely to recover an above-average number of transplantable organs per donor than low-volume hospitals in this study. The study included data from 4,427 donors across 384 hospitals. High-volume hospitals had an organ yield (ie, rate of…

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Editor's Note Using a computerized mathematical model, Johns Hopkins researches investigated whether they could improve heart and lung transplants by transferring patients from low- to high-volume transplant centers. Among the findings: For heart transplants, 10 lives were saved after one center closure, and 240 lives were saved after up to…

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Editor's Note Researchers at Penn Medicine, Philadelphia, are conducting a clinical trial to test the effect of administering antiviral therapy to organ recipients after being transplanted with kidneys infected with the hepatitis C virus (HCV). The first participant received a kidney transplant in July, and after being treated with Zepatier…

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Editor's Note Liver transplant candidates who are the sickest and should be first in line for a donor liver are increasingly being removed from the wait list because they are considered too sick to transplant, finds this study. Between 2007 and 2012, more than 4,300 patients were taken off the…

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Editor's Note In this meta-analysis, organ recipients who had cancer before receiving an organ transplant had higher rates of mortality and new cancers than organ recipients who had not had cancer. Organ recipients with previous cancers had a 1.5 times greater risk of dying from any cause, 3 times higher…

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Editor's Note Surgeons at the University of Pennsylvania and Johns Hopkins University hospitals will transplant kidneys from donors with hepatitis C virus (HCV) as part of a clinical trial this spring, STAT news reports. The recipients will be given a 12-week course of antiviral therapy after the transplant in hopes…

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Editor's Note Patients who underwent desensitization therapy and received kidney transplants from HLA-incompatible live donors had a substantial survival benefit, compared with patients who did not undergo transplantation or those who waited for transplants from deceased donors, this study finds. Researchers from Johns Hopkins, Baltimore, enrolled 1,025 patients at 22…

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Editor's Note Obtaining organs from deceased donors in a freestanding facility dedicated to organ recovery costs much less and leads to higher numbers of transplantable organs, this study finds. Researchers evaluated 6 years of data from the nation’s first freestanding organ recovery facility located in St Louis and owned and…

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Editor's Note A team of Cleveland Clinic surgeons on February 24 performed the nation’s first uterus transplant. The 9-hour procedure was performed on a 26-year old patient who had uterine factor infertility. The transplanted uterus came from a deceased organ donor. Further information will be released this week in a…

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