Study: Antibiotic de-escalation reduces adverse outcomes in patients with sepsis
Editor's Note A study analyzing data from 124,577 suspected sepsis cases across 236 US hospitals found that antibiotic de-escalation—switching to narrower-spectrum antibiotics or stopping broad-spectrum antibiotics—occurred in less than 30% of cases but was associated with improved patient outcomes, according to December 6 report from the Center for Infectious Disease…
Study: Bariatric surgery outperforms GLP-1s in slowing CKD progression in patients with diabetes, obesity
Editor's Note Bariatric surgery significantly reduces the progression of chronic kidney disease (CKD) in patients with type 2 diabetes and obesity compared to those on GLP-1 diabetes medications, according to a study from Cleveland Clinic. Published in Annals of Surgery and detailed in a September 20 announcement from Cleveland Clinic,…
Study: Infection risk unaffected by colonoscopy, joint replacement timing
Editor's Note A study published May 7 in JAMA Open found no significant risk of periprosthetic joint infection (PJI) when colonoscopy is performed within one year of total joint arthroplasty (TJA), whether the colonoscopy was done before or after the surgery. However, certain comorbidities such as kidney and pulmonary disease,…
Study: Ozempic slows disease, reduces cardiovascular risk in CKD, diabetes patients
Editor's Note Semaglutide, the active ingredient in Ozempic diabetes treatment and Wegovy weight-loss treatment, outperformed a placebo and demonstrated capacity to reduce risk of death from kidney-related or cardiovascular causes in a recent study of patients with type 2 diabetes and chronic kidney disease spearheaded by manufacturer Novo Nordisk. Published…
Majority of American adults have CKM syndrome, at risk for heart disease
Editor's Note Nine out of 10 American adults have Cardiovascular, kidney, and metabolic syndrome (CKM)—interrelated factors that progress to heart disease—and almost 10% already have heart disease, according to a report published in JAMA by Brigham and Women’s Hospital and Harvard Medical School in Boston. HealthDay news reported on the…
New hope for Black kidney disease patients awaiting organ transplants
Editor's Note A standard kidney function test has been underestimating the seriousness of disease in Black patients, delaying their eligibility for transplants, The Associated Press reported March 31. Now, that test is changing – and Black patients awaiting kidneys are moving up the list. Among other factors, transplant eligibility is…
Study: COVID-19 could elevate risk of surgical mortality, complications
Editor's Note Due to its impact on a variety of organ systems, COVID-19 could elevate perioperative risks even among patients with mild symptoms, according to a study published in the February 2024 issue of Anesthesiology. Focused on patients presenting for elective inpatient surgery between April 2020 and April 2021, the…
New epigenetic clock provides clues to accelerated aging in chronic kidney disease
Editor's Note Researchers from Europe used an epigenetic clock to accurately measure biological aging in a clinical setting, Wiley October 12 reports. The study, titled "Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing," was published in the Journal of Internal Medicine. The researchers…
Effect of kidney disease on COVID-19 outcomes
Editor's Note This study from Columbia University Medical Center, New York City, which was presented November 5 at the ASN [American Society of Nephrology] Kidney Week 2022 in Orlando, examines the effect of kidney disease and other conditions on COVID-19 outcomes during four waves of the pandemic in New York…
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