Editor's Note In this study, researchers from Henry Ford Health System in Michigan found that hydroxychloroquine alone decreased the mortality hazard ratio of COVID-19 by 66%, and hydroxychloroquine with azithromycin decreased the ratio by 71%, compared to neither treatment. The vast majority of the 2,541 COVID-19 patients included in the…

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Hospitals have long dominated the realms of infection control and antibiotic overuse. Ambulatory surgery centers (ASCs), which typically release patients the same day of a procedure, use antibiotics less frequently than other facilities, and most do not have an antimicrobial stewardship program. However, some ASC leaders and organizations are encouraging…

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Editor's Note More than 2.8 million antibiotic-resistant infections occur in the US each year, resulting in more than 35,000 deaths, according to a new “Antibiotic Resistance Threats in the United States 2019” report from the Centers for Disease Control & Prevention (CDC). The CDC also notes that 223,900 cases of…

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Editor's Note Social risk factors were inconsistently associated with surgical site infection (SSI) rates after colectomy or abdominal hysterectomy in this study. In this analysis of 149,741 patients, Medicaid status (a marker for poverty) and living in a low-income zip code were linked to higher SSI rates after colectomy. For…

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Enhanced Recovery After Surgery (ERAS®) is a comprehensive, multifaceted, and multidisciplinary approach to the care of the surgical patient. ERAS bundles evidence-based elements to facilitate a faster recovery with fewer complications.1 Spanning the continuum of perioperative care, ERAS elements include: • patient engagement and education • preoperative optimization of nutrition…

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Editor's Note Because of the potential risk of selecting mutants carrying genes for cross-resistance to chlorhexidine gluconate (CHG) and antibiotics, it is advisable to reserve the use of CHG for purposes other than hand hygiene, this study finds. A review of studies showed no significant difference in healthcare-associated infection rates…

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Editor's Note Hospitals that perform better on measures to prevent postoperative complications also have better performance on measures of profitability, this study finds. Improved patient safety performance was associated with higher net patient revenue for five of seven Surgical Care Improvement Project (SCIP) measures, including starting and stopping preventive antibiotics…

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Editor's Note In this multi-center study, longer durations of surgical prophylaxis did not result in further reductions in surgical site infections (SSIs) but were associated with increasing adverse events. Of 79,058 surgical patients in the VA healthcare system, SSI was not associated with duration of prophylaxis, but odds of acute…

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Editor's Note The Joint Commission on January 9 announced that it is seeking feedback on its newly proposed requirements for antimicrobial stewardship at Medication Management (MM) standard MM.09.01.03. The requirements apply to ambulatory healthcare organizations and office-based surgery practices. The proposed requirements align with current recommendations from scientific and professional…

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Editor's Note Antimicrobial treatment of asymptomatic organisms identified in preoperative urine cultures was not associated with reductions in the risk for postoperative infections, including urinary tract infections (UTIs) and surgical site infections (SSIs), this study finds. In this analysis of 68,265 patients in 109 Veterans Affairs hospitals who had cardiac,…

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