Editor's Note A pair of immunotherapy drugs administered before surgery significantly diminished tumor size without serious safety concerns in patients with mismatch repair-deficient (dMMR) colorectal cancer, according to a study published in the New England Journal of Medicine. Healthline reported the news June 8. Constituting 10-15% of cases, dMMR cancer…

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Editor's Note Robotic liver surgery can be performed safely as an outpatient procedure, according to findings from the City of Hope cancer research organization in Duarte, California. According to a June 10 press release, the study analyzed data of 307 patients who underwent outpatient robotic liver surgery (defined as requiring…

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Editor's Note In esophageal cancer, combining preoperative and postoperative chemotherapy lead to better outcomes, fewer deaths, and higher likelihood of complete tumor regression than preoperative chemotherapy alone, according to a randomized clinical trial. US News and World Report reported the news June 4. Led by Dr. Jens Hoeppner from the…

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Editor's Note A fluorescent marker dye that attaches to a protein specific to prostate cancer cells could help surgeons identify and remove them in real time, BBC News reported June 9. Developed by researchers from the University of Oxford in the UK, the dye reportedly performed promisingly in a trial…

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Editor's Note Artificial intelligence (AI)-fueled analysis of electronic health records suggests that clinical guidelines for de-escalating surgery should be extended to younger breast cancer patients. Conducted by University of Pittsburgh and UPMC Hillman Cancer Center researchers and published in JCO Clinical Cancer Informatics, the analysis suggests that “surgery involving sentinel…

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Editor's Note An AI model that outperformed MRI and ultrasound in identifying patients with axillary breast cancer metastasis shows the technology’s potential to reduce the need for needle or surgical biopsies, according to developers at UT Southwestern Medical Center. In a May 21 report on their new AI model, researchers…

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Editor's Note New evidence from skulls in a university collection reveals that brain surgery dates back millennia—potentially as far back as 4,o00 years ago. CNN reported the news May 29. Researchers expressed uncertainty in some cases whether marks on the skulls indicated surgery to treat a living person or an…

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Editor's Note A comprehensive systematic review and meta-analysis, published by JAMA Network on May 24 and encompassing 81 studies and over 24.9 million patients, shed light on the signs and symptoms associated with early-onset colorectal cancer (EOCRC) and highlighted significant delays in diagnosis. The analysis identified the most common presenting…

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Editor's Note Although robotic-assisted laparoscopic surgery (RLS) and conventional laparoscopic surgery (CLS) offer similar survival outcomes for sigmoid colon cancer, RLS harvests comparatively more lymph nodes, according to a study published May 10 in the Journal of Robotic Surgery. According to a May 15 report on the study in The…

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Editor's Note By putting the patient into deeper sedation during colonoscopy, propofol could help doctors find difficult-to-spot, potentially cancerous “serrated” polyps, according to a study published April 17 in Anesthesiology. As an alternative to moderate, “conscious” sedation, propofol facilitates a more thorough exam that is more likely to identify serrated…

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