EHR ‘nudge’ reduces unnecessary axillary surgery in older breast cancer patients
Editor's Note An electronic health record (EHR)-based nudge could significantly reduce low-value axillary surgeries in older women with early-stage breast cancer, researchers reported July 17 in JAMA Surgery. Conducted across eight clinical settings, the initiative significantly cut the rates of low-value sentinel lymph node biopsies (SLNB) by nearly 50% over…
Voice-restoring larynx transplant shows progress for rare cancer treatment
Editor's Note A Massachusetts man, Marty Kedian, regained his voice after a pioneering larynx transplant at the Mayo Clinic in Arizona, The Associated Press (AP) reported July 9. According to the article, Kedian is only the third person in the U.S. to receive a total larynx transplant and the first…
Reassessing colonoscopy surveillance: Early- vs average-onset colorectal cancer
Editor's Note Early-onset colorectal cancer (EO-CRC), diagnosed before age 50, is increasing in incidence worldwide. Despite existing postoperative colonoscopy surveillance strategies, the optimal intervals for EO-CRC patients are unclear due to limited long-term data. This study, titled “Early-onset Colorectal Cancer Patients Do Not Require Shorter Intervals for Post-surgical Surveillance Colonoscopy”…
AI outperforms radiologists in detecting clinically significant prostate cancer
Editor's Note In a recent study, an artificial intelligence (AI) system detected more clinically significant prostate cancers and fewer indolent cancers than human radiologists reading MRIs, MedPage today reported June 13. The MedPage report covers a study published in Lancet Oncology that, according to researchers, “provided evidence that AI systems,…
The rise of AI in radiology—and what the future holds
When it comes to the adoption of artificial intelligence (AI) in medicine, radiology is leading the charge. As of May 13, 2024, the US Food and Drug Administration (FDA) had approved nearly 900 AI- and machine learning (ML)-enabled devices, and the vast majority of them are in radiology. One example…
Study: Immunotherapy offers significant benefits for dMMR colorectal cancer
Editor's Note A pair of immunotherapy drugs administered before surgery significantly diminished tumor size without serious safety concerns in patients with mismatch repair-deficient (dMMR) colorectal cancer, according to a study published in the New England Journal of Medicine. Healthline reported the news June 8. Constituting 10-15% of cases, dMMR cancer…
Study: Liver surgery safe for outpatient settings
Editor's Note Robotic liver surgery can be performed safely as an outpatient procedure, according to findings from the City of Hope cancer research organization in Duarte, California. According to a June 10 press release, the study analyzed data of 307 patients who underwent outpatient robotic liver surgery (defined as requiring…
Study: Combined preoperative, postoperative chemotherapy improves esophageal cancer outcomes
Editor's Note In esophageal cancer, combining preoperative and postoperative chemotherapy lead to better outcomes, fewer deaths, and higher likelihood of complete tumor regression than preoperative chemotherapy alone, according to a randomized clinical trial. US News and World Report reported the news June 4. Led by Dr. Jens Hoeppner from the…
Glowing dye could improve detection, removal of prostate cancer cells
Editor's Note A fluorescent marker dye that attaches to a protein specific to prostate cancer cells could help surgeons identify and remove them in real time, BBC News reported June 9. Developed by researchers from the University of Oxford in the UK, the dye reportedly performed promisingly in a trial…
AI analysis suggest breast cancer surgery “may do more harm than good” for middle-aged patients
Editor's Note Artificial intelligence (AI)-fueled analysis of electronic health records suggests that clinical guidelines for de-escalating surgery should be extended to younger breast cancer patients. Conducted by University of Pittsburgh and UPMC Hillman Cancer Center researchers and published in JCO Clinical Cancer Informatics, the analysis suggests that “surgery involving sentinel…
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