Tag: clinical trial

Alternative to mitral valve surgery shows promise, but research criticized

Editor's Note Although data suggest transcatheter edge-to-edge repair (TEER) using the MitraClip device may offer similar outcomes to mitral valve surgery in patients with heart failure and functional mitral regurgitation (FMR), experts have criticized the research, TCT MD reported September 1. Presented at the recent European Society of Cardiology (ESC)…

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By: Matt Danford
September 23, 2024
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Flexibility for clinicians in managing RAS inhibitors in noncardiac surgery

Editor's Note A new study, the Stop-or-Not Trial, has found no significant difference in outcomes for patients undergoing noncardiac surgery who either continued or discontinued their renin-angiotensin system (RAS) inhibitor therapy, MedPage Today August 31 reports. The randomized clinical trial, which included over 2,200 patients, reported the rate of death…

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By: Tarsilla Moura
September 3, 2024
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Brain implant leverages AI, neural sensors to restore speech for ALS patient

Editor's Note Researchers at UC Davis have developed a brain-computer interface (BCI) implant that has successfully restored speech in a patient with amyotrophic lateral sclerosis (ALS), whose ability to speak had deteriorated, Fierce Biotech reported August 15. The breakthrough was achieved using neural sensors from Blackrock Neurotech and AI-driven text-to-speech…

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By: Matt Danford
August 30, 2024
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Origami-inspired brain implants hold promise for Epilepsy surgery

Editor's Note Human trials may begin soon on patients in the UK using tiny, folding brain implants that could improve epilepsy surgery, according to an article published August 12 in The Telegraph. Developed by scientists at Oxford and Cambridge, who published their research in the journal Nature Communications, the implants…

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By: Matt Danford
August 29, 2024
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Neurosurgery trial: Early evacuation improves long-term hemorrhage outcomes

Editor's Note Medical management care with evacuation surgery could yield better 180-day outcomes than without in patents treated within 24 hours for acute intracerebral hemorrhage, according to study results covered in an April 10 MedPage Today report. The ENRICH (Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH)) trial is a multicenter,…

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By: Matt Danford
April 18, 2024
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Study recommends against polyhexanide wound irrigation during open abdominal surgery

Editor's Note Although intraoperative wound irrigation is a common practice worldwide for preventing surgical site infections, a recent study suggests irrigation with polyhexanide solution should not be recommended as standard clinical practice in open clean-contaminated surgical procedures. Published February 21 in Jama Surgery, the study cautions that additional trials are…

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By: Matt Danford
March 28, 2024
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Moderna mRNA RSV vaccine proves effective for older adults

Editor’s note Moderna’s mRNA-based RSV vaccine is effective in preventing RSV-associated lower-respiratory tract disease in adults aged 60 an older, according to randomized phase II-III trial results published December 14 in The New England Journal of Medicine. Results also confirmed the safety of a single dose of the vaccine, researchers…

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By: Matt Danford
December 22, 2023
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Senate appoints oncologist, cancer researcher as NIH director

Editor's Note The US Senate has appointed Monica Bertagnolli, MD, as the new director of the National Institutes of Health (NIH), the agency’s first permanent leader in nearly 2 years and the second woman to hold the post. She is expected to face significant scrutiny from lawmakers, Chief Healthcare Executive…

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By: Brita Belli
November 17, 2023
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Concerted push for greater diversity in medical studies ongoing

Editor's Note Although Congress first required the National Institutes of Health to include more women and people of color in medical studies in 1993, progress has been slow until recently. Now, researchers are making a concerted effort to diversify medical studies, The Wall Street Journal (WSJ) November 16 reports.  According…

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By: Brita Belli
November 16, 2023
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Video laryngoscopy leads to higher success rates than direct laryngoscopy

Editor's Note Video laryngoscopy was found to lead to higher intubation success rates over direct laryngoscopy in critically ill adult patients, an August 2023 randomized controlled trial published by the The New England Journal of Medicine shows. The findings were consistent whether they were intubated in an emergency room or…

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By: Brita Belli
October 30, 2023
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