Editor's Note Research reveals nearly 10% of patients treated with prescription opioid painkillers develop opioid dependency or opioid use disorder (OUD), Healio reported on August 13. Additionally, nearly 30% of patients exhibit signs and symptoms indicating potential OUD. Originally published in the journal Addiction, the data are from a systematic…

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Editor's Note A shuttered bariatric surgery center in Oklahoma last month is just one example of how the rise of Glucagon-like peptide-1 (GLP-1) agonists are reshaping health systems’ investments, Axios reported August 13. Rather than “massive hospital towers with cardiology clinics, dialysis beds and joint replacement centers,” the focus is…

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Editor's Note The US Food & Drug Administration (FDA) has approved immunotherapy durvalumab for perioperative treatment of resectable non-small cell lung cancer (NSCLC), according to an August 15 announcement. The approval is for durvalumab (Imfinzi, AstraZeneca) in combination with platinum-based chemotherapy as a neoadjuvant treatment, followed by durvalumab alone as…

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Editor's Note Propofol research published in the journal Neuron has broader implications for enabling more precise, safer doses of anesthesia, according to an August 14 report in Anesthesiology News. According to the article, anesthesiologists tend to use higher doses of anesthetics because they rely on indirect measures, such as heart…

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Editor's Note Medicare’s first negotiations on 10 top-selling prescription drugs for older Americans will save the US government $6 billion in the first year, according to an August 15 article in Reuters. Enabled by President Joe Biden’s 2022 Inflation Reduction Act, negotiations for drugs used by Medicare—which covers 66 million…

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Editor's Note For diabetic patients with obesity and chronic kidney disease (CKD), metabolic bariatric surgery could protect the kidneys better than therapy with glucagon-like peptide-1 receptor agonists (GLP-1RA), according to research published in the September issue of the Annals of Surgery. Conducted at a large US health system, the study…

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Editor's Note Many youths continue to take opioids months after undergoing surgery, according to a recent multi-institutional study published in JAMA Network. Medical Xpress covered the news July 11. Conducted by researchers from CHOP, Massachusetts General Hospital, University of Pennsylvania, and Stanford Medicine, the study found 1 in 6 youths…

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Editor's Note In a new guidance document for manufacturers of pharmaceuticals and biopharmaceuticals, The Association for the Advancement of Medical Instrumentation (AAMI) has released a new guidance document updating best practices for radiation sterilization validation and routine control of single-use systems. The document, AAMI CR513:2024; Guidance on radiation sterilization validation and…

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Editor's Note Intraoperative infusion of dexmedetomidine (DEX) could help improve glycemic control and reduce insulin requirements in diabetic patients undergoing cardiac surgery, according to a July 25 article in Medical Dialogues. The article focuses on a prospective observational study published in the journal Annals of Cardiac Anesthesia. The study included…

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Editor's Note Erin Fox, senior pharmacy director at University of Utah Health who has been monitoring drug shortages for over 20 years, spoke to AP News in June of her concerns. Currently, the situation is worse than ever, with total active shortages hitting an all-time high of 323 (with 48…

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