Study: Microglia help awaken the brain from anesthesia, protect neurons from aftereffects
Editor's Note A new study finds that the same cells that are involved in preventing damage to the central nervous system – called microglia – help to awaken the brain following anesthesia. The findings appeared January 4 in the journal Nature. Using electron-microscopy-based synaptic reconstruction, the researchers could see the…
Soundproof headphones alleviate orthopedic surgery discomfort
Editor's Note: Soundproof headphones may improve physiological indices and decrease length of stay in the PACU for orthopedic surgery patients under spinal anesthesia, according to a study published January 4 in the Journal of PeriAnesthesia Nursing. Aiming to investigate the effect of wearing soundproof headphones during orthopedic surgery under spinal…
Study: Less-painful propofol alternative non-inferior in general anesthesia induction
Editor's Note: HSK3486 injectable emulsion (ciprofol) is noninferior to propofol in successful induction of general anesthesia, according toa study published December 13 in Anesthesiology. The study also confirmed prior data indicating HSK3486 causes substantially less injection-site pain. The multicenter, randomized (2:1), double-blind, propofol-controlled, phase-4 study evaluated 255 adults undergoing elective surgery…
Testing shows promise for automated anesthesia monitoring, delivery system
Editor’s Note A new automated delivery system for anesthesia that has been effectively tested in monkeys could eventually be used by doctors to identify and deliver the right dose of drugs in people. The findings appeared October 31 in PNAS (Proceedings of the National Academy of Sciences of the United…
Motor vehicle crash risk after general surgery
Editor's Note Because there is limited data to guide return to driving recommendations for patients after surgery, researchers at the Massachusetts General Hospital, Boston, performed this nested case-crossover study to find if the risk of a motor vehicle crash increases after surgery, compared to before. The analysis included 70,722 licensed…
Study: Risk of higher oxygen levels under general anesthesia
Editor's Note An observational study, led by researchers at Vanderbilt University Medical Center (VUMC) and released on November 30 in The BMJ, the flagship journal of the British Medical Association, shows that higher levels of oxygen given to patients under general anesthesia can add risk of injury, VUMC reported on November…
Postop effect of vaccination status, mode of anesthesia on COVID-19 patients
Editor's Note This study by researchers at Kaiser Permanente and the University of California, San Francisco-East Bay, Oakland, finds that having a surgical procedure shortly after COVID-19 infection was not associated with higher risks in fully vaccinated patients or those who did not have general anesthesia. The analysis included 228,913…
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