Editor's Note Preliminary findings in Moderna’s (Cambridge, Massachusetts) COVID-19 trial show the vaccine elicits strong immune system responses in older adults similar to responses in younger recipients, and adverse events associated with the vaccine are mainly mild or moderate. In its expansion to include older adults, the trial enrolled 40…

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Editor's Note This study, led by economists from Washington University in St Louis, finds that the ideal COVID-19 vaccine policy should emphasize age more than work-exposure risk for vaccination priority. To provide a best-practice scenario to supplement a vaccine distribution strategy, the researchers tracked eight age groups in more than…

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Editor's Note In this review article, researchers from the US, UK, Netherlands, and Australia discuss current evidence on the pathophysiology, transmission, diagnosis, and management of COVID-19. Among their findings: COVID-19 is spread primarily via respiratory droplets during close face-to-face contact. Infection can be spread by asymptomatic, presymptomatic and symptomatic carriers.…

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Editor's Note Patients having surgery after contracting COVID-19 are at greatly increased risk of postoperative death, this study finds. Researchers examined data for 1,128 patients from 235 hospitals in 24 countries. Overall 30-day postoperative mortality was 23.8%. Mortality was high across all subgroups including: elective surgery, 18.9% emergency surgery, 25.6%…

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Editor's Note The Centers for Medicare & Medicaid Services (CMS) on June 1 unveiled enhanced enforcement actions for nursing homes with violations of infection control practices. The enhanced and targeted accountability actions are based on trends in recent data regarding the incidence of COVID-19 in nursing homes and infection control…

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Editor's Note The Centers for Disease Control and Prevention on May 1 updated its weekly surveillance summary of COVID-19 activity in the US ending April 25. Among the updates: The percentage of specimens testing positive for SARS-CoV-2 decreased at public health and commercial laboratories and remained similar at clinical labs.…

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Editor's Note Many adults with comorbid conditions lacked critical knowledge about COVID-19, and, despite concern, they did not change their routines or plans, this study finds. In this cross-sectional survey of 630 adults aged 23 to 88 years, and living with one or more chronic conditions: 24.6% were “very worried”…

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Editor's Note The Centers for Disease Control and Prevention (CDC) on April 14 released a Morbidity and Mortality Weekly Report on the characteristics of healthcare workers (HCW) with COVID-19 in the US. From February 12 to April 9, 2020, there were 9,282 cases of COVID-19 reported among HCWs. The median…

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Editor's Note This study represents the first description of critically ill patients infected with SARS-CoV-2 in the US. These patients had a high rate of acute respiratory distress syndrome (ARDS) and a high risk of death, similar to patients in China. A total of 21 patients with a mean age…

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Editor's Note The Risk Analysis Index (RAI) frailty screening tool, which was previously validated in the VA health system, can be efficiently implemented in multispecialty, multihospital healthcare systems to predict adverse postoperative outcomes, including mortality, readmission, and extended hospital stays, this study finds. From July 1 to December 31, 2016,…

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