Editor's Note This phase 3, double-blind, randomized, placebo-controlled study led by researchers at the University of Minnesota, Minneapolis, finds that none of three medications evaluated—metformin, ivermectin, or fluvoxamine—prevented the occurrence of a primary event—hypoxemia, an emergency department (ED) visit, hospitalization, or death—associated with COVID-19. Of 1,323 patients analyzed, a primary…

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Editor's Note The Food and Drug Administration on August 29 identified the recall by Intera Oncology of its Intera 3000 Hepatic Artery Infusion Pump as Class I, the most serious. The company is recalling the pumps after receiving reports from clinicians that the pumps were delivering medication faster than expected.…

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Editor's Note This study led by researchers at the University of North Carolina School of Medicine, Chapel Hill, finds that nearly 72% of healthcare providers in US safety net practices experienced either mild or intense levels of moral distress during the first year of COVID-19 because of issues with patient…

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Editor's Note This study (CRISTAL randomized trial) from Australia finds that aspirin compared with enoxaparin resulted in significantly higher rates of venous thromboembolism (VTE) after total hip or knee arthroplasty. This cluster-randomized, crossover trial included 9,711 patients in 31 hospitals in Australia—5,675 in the aspirin group and 4,036 in the…

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Editor's Note The Food and Drug Administration on August 25 identified the recall by Medtronic of its HeartWare Ventricular Assist Device (HVAD) system batteries as Class I, the most serious. Medtronic is recalling the batteries because they may experience electrical faults that cause them to unexpectedly fail. A similar recall…

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Editor's Note This meta-analysis led by researchers in Spain finds that regular physical activity is associated with a lower risk of COVID-19 infection, severity, and mortality. The analysis included 1,853,610 adults from multiple countries worldwide—54% were women, and the average age was 53. Compared with physically inactive individuals, those who…

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Editor's Note The Food and Drug Administration (FDA) on August 22 posted the Hospira Inc (a Pfizer company) recall of one lot of Propofol Injectable Emulsion (containing Benzyl alcohol), 100 mL single patient use glass fliptop vials, lot EA7470. The recall was initiated because of visible particulates observed in two…

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Editor's Note The Food and Drug Administration (FDA) on August 19 identified the recall by Medtronic of its Cobalt XT, Cobalt, and Crome Implantable Cardioverter Defibrillators (ICDs) and Cardiac Resynchronization Therapy Defibrillators (CRT-Ds) as Class I, the most serious. The devices are being recalled because of reports of short circuit-protection…

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What if unprofessional behavior in the OR could be managed through something as simple as an informal chat over a cup of coffee? This peer-to-peer approach advocated by Vanderbilt University School of Medicine led to the development of two well-established, scientifically validated programs designed to offset unprofessional behavior: the Patient…

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Editor's Note This study led by researchers at Cedars-Sinai Medical Center, Los Angeles, finds that more than half of adults with recent Omicron infection analyzed were unaware of their infectious status. Of 210 adult employees or patients at Cedars-Sinai Medical Center with serological evidence of recent Omicron variant infection: 92…

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