Stem cell therapy is poised to revolutionize regenerative medicine. As these therapies advance, they may alter or even replace certain invasive surgical procedures. Already undergoing advanced clinical trials, orthopedic applications are likely candidates for attracting the earliest adopters. Results so far indicate significant potential for providing alternatives to implants, grafts,…

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Editor's Note Psilocybin therapy significantly reduces symptoms of depression in frontline clinicians who experienced psychological distress during the COVID-19 pandemic, according to a randomized clinical trial published December 5 in JAMA Network Open.   The trial enrolled 30 clinicians, including physicians, advanced practice practitioners (APPs), and nurses, who provided frontline care…

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Editor's Note Findings from The ARRC II study show using advanced recovery room care (ARRC) for medium-risk surgical patients significantly reduces 18-month postoperative mortality compared to standard ward care. As detailed in a December 11 research letter in JAMA Surgery, this benefit appears linked to minimizing early postoperative complications, which…

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Editor's Note An analysis of trends in body mass index (BMI) and obesity among US adults from 2013 to 2023 reveals a slight but significant decline in obesity prevalence in 2023, marking the first decrease after years of steady increases. The findings are detailed in a December 13 JAMA Health…

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Editor's Note Active monitoring for certain breast cancer patients offers similar outcomes to surgery with fewer side effects, according to research detailed in a December 16 article from Oncology News Central. Presented at the 2024 San Antonio Breast Cancer Symposium and published in JAMA, The COMET trial supports the safety…

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Editor's Note Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative early breast cancer provides noninferior outcomes compared to undergoing the procedure, MedPage Today reported December 13. Presented at the San Antonio Breast Cancer Symposium and published in the New England Journal of Medicine, the INSEMA trial found…

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Editor's Note Perioperative immunotherapy is reshaping treatment strategies for early-stage non-small cell lung cancer (NSCLC) without actionable mutations, according to Dr. Roy S. Herbst of Yale Cancer Center. In a recent interview with OncLive, the oncology expert highlighted the promise of neoadjuvant and adjuvant therapies to improve outcomes for these…

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Editor's Note Leading medical journals vary significantly in guidance addressing the use artificial intelligence (AI) in medical research, according to an analysis published December 3 in JAMA Network Open.   The study categorized journals’ attitudes toward AI-assisted peer review into three groups: prohibition, limited use with conditions, and lack of explicit…

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Editor's Note A recent study developed and validated an artificial intelligence (AI) model leveraging natural language processing (NLP) and machine learning to significantly improve prediction accuracy for surgical case length. Published November 29 in the journal Surgery, the findings show promise for using AI as an alternative to current methods…

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Editor's Note Non-operative management (NOM) with antibiotics for pediatric uncomplicated appendicitis is both less expensive and slightly more effective than urgent laparoscopic appendectomy over a one-year period, according to a study published November 19 in the Journal of the American College of Surgeons. The findings support the viability of NOM…

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