Editor's Note In preliminary results of this study from the University of Oxford, UK, a low-cost steroid, dexamethasone, reduced deaths by up to one third in hospitalized patients with severe respiratory complications of COVID-19. A total of 2,104 patients were randomized to receive dexamethasone 6 mg once per day for…

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Editor's Note COVID-19 causes a global threat to the entire nervous system, including the brain, spinal cord, and nerves, and neurologic symptoms may appear before symptoms, such as fever, cough, or respiratory problems, finds this study from Northwestern Medicine in Chicago. This analysis found that about half of hospitalized patients…

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Editor's Note The Mayo Clinic on June 11 announced that it had launched a new SARS-CoV-2 neutralizing antibody test that will be available to select labs, blood banks, and biopharma clients in late June. The test measures the level of neutralizing antibodies against SARS-CoV-2, the virus that causes COVID-19. Neutralizing…

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Editor's Note The Food and Drug Administration (FDA) on June 10 released a COVID-19 update announcing the following actions taken in its response to the pandemic: The FDA and National Institutes of Health have updated the CURE ID crowd-sourcing app to make it easier for healthcare providers to share their…

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Editor's Note The Lancet and New England Journal of Medicine (NEJM) have both retracted COVID-19 treatment studies because of concerns about the validity of the data and how the research was conducted by Chicago-based Surgisphere Corp, the June 4 Medscape Medical News reports. Authors of the Lancet study, which was…

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Editor's Note The fatality rate in the US for those infected with SARS-CoV-2 who show symptoms is 1.3%, this study from the University of Washington finds. To build county-by-county models, the researchers used publicly reported national COVID-19 data for 116 counties in 33 states. A rate variable was constructed by…

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Editor's Note In this study, researchers from Beth Israel Deaconess Medical Center in Boston demonstrated that six candidate DNA vaccines induced neutralizing antibody responses and protected against SARS-CoV-2 in rhesus monkeys. For the study, researchers immunized 25 adult rhesus monkeys with the investigational vaccines, and 10 animals received a sham…

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Editor's Note An international study will include more than 30,000 front-line healthcare workers to assess whether chloroquine can prevent COVID-19 or decrease its severity. Washington University School of Medicine in St Louis is the clinical coordinating center for the study. Healthcare workers will be divided randomly into four groups. Three…

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Editor's Note The National Institutes of Health (NIH) on May 14 announced that it is enrolling adults with mild to moderate COVID-19 in a study of treatment with hydroxychloroquine and azithromycin. The Phase 2b trial is enrolling around 2,000 adults across the US. Participants must have confirmed infection with SARS-CoV-2…

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Editor's Note The University of Kentucky (UK) announced May 11 that researchers have begun antibody testing that will help to understand what immunity to COVID-19 really means. Several research labs within the UK College of Medicine and Pharmacy will be testing antibodies of recovered COVID-19 patients to see how long…

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